Warburton’s place in the starting line-up is taken by Italy international Manoa Vosawai.
A revamped back row will see Josh Turnbull will play at blindside flanker, Ellis Jenkins at openside flanker and Vosawai play at Number Eight.
Macauley Cook is called up to the replacements bench for the Pool 3 encounter between two unbeaten sides.
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Cardiff Blues: 15 Blaine Scully, 14 Alex Cuthbert, 13 Rey Lee-Lo, 12 Gavin Evans, 11 Tom James, 10 Rhys Patchell, 9 Lloyd Williams; 1 Gethin Jenkins (c), 2 Kristian Dacey, 3 Taufa’ao Filise, 4 Jarrad Hoeata, 5 James Down, 6 Josh Turnbull, 7 Ellis Jenkins, 8 Manoa Vosawai
Replacements: 16 Matthew Rees, 17 Sam Hobbs, 18 Dillon Lewis, 19 Lou Reed, 20 Macauley Cook, 21 Tavis Knoyle, 22 Jarrod Evans, 23 Dan Fish